Adhesion to fibronectin augments tumor necrosis factor production by human alveolar macrophages.

1 OOS 36th Annual Aspen Lung Conference time I sc’mmc’e of a grouup 2 PLA,, no sPLA, mnRNA was dletec’tath)le by RT-PCR iui resting or primed PMN or imi FII,-6() cells (tumsciif’f’eremutiatecl and alt 3 amid 5 dlaivs d)f differeumtiattioum), sumggestimmg thmatt time PM N enzy’mne is distiumc’t l’roumi time kmiowmu group 2 sPLA, idlemmtifiedi imi other cells (platelets, liver celis, etc). To study reguulatioum of tlse PLA,(s) atctivated in primmied cells, we clevelopeel a model of PM N perusmeaubihizech with Staphmvtococceus a tcixiui to study regulatiomi of PLA,s with tow ummole’cuulatr weight c’ofauctors. .2Usimmg cells labelled vithi 1l-1-AA, we hmacl previouustv f’oiuumd thast imi iumsprimnecl,